Week

Lab Topic / Experiment

Techniques/Principles

Reading / Assignments

1

Sept 29

Introduction/Check-in/Safety

Handout :

 Biosynthesis of Ethanol (Part I: Preparation of Ethanol)

Laboratory Safety

Keeping a Laboratory notebook

Techniques in Organic Chemistry

Ch 1: Safety in the Lab (1.1-1.4)

Ch 2: Laboratory Glassware (2.1-2.2, 2.4)

Ch 3: Lab Notebook (3.1, 3.2)

Ch 4: Handbooks/Online Resources (4.1-4.2)

Green Organic Chemistry

Ch 1: Introduction (1.1-1.3)

Ch 4: Sources of Info about Chemical Hazards

Ch 11: Preface to the Exp Section (11.1-11.4)

2

Oct  6

Handout:  Biosynthesis of Ethanol (Part II: Purification of Ethanol by Distillation)

Distillation (simple & fractional)

Green Principles

Intro to 12 steps of Green Chem

Catalysts

Design for Degradation

Renewable Feedstocks

Techniques in Organic Chemistry

Ch 6: Heating & Cooling Methods (6.1-6.4)

Ch 11: Simple distillation (11.1-11.3a)

Fractional Distillation (11.4)

Azeotropic Distillation (11.5)

3

Oct  13

IR Training

GOC Exp 1: Solventless Aldol Condensation (begin)

Functional Group Review

IR of Liquids & Solids

Green Principles

Solventless Reactions

Atom Economy

Techniques in Organic Chemistry

Ch 18: Infrared Spectroscopy

Ch 5:Measuring Mass and Volume (5.1-5.2)

Ch 1: Chemical Toxicology/Safety (1.5-1.6)

Green Chem & Atom Economy (1.7-1.9)

4

Oct  20

GOC Exp 1: Solventless Aldol Condensation (finish)

Melting points (solids & mixtures)

Recrystallization

Techniques in Organic Chemistry

Ch 10: Melting Points:

5

Oct  27

Lab Quiz

GOC Exp 2 Bromination of an Alkene

Vacuum Filtration

Melting Point Determination

Green Principles

Safer Solvents & Reagents

Atom Economy

Techniques in Organic Chemistry

Ch 9: Review Recrystallization

Ch 9.5: Vacuum Filtration

Green Organic Chemistry

Ch 10: Green Chemistry Metrics

6

Nov  3

GOC Exp 3: A Greener Bromination of Stilbene

Reflux

Green Principles

Relative nature of “green”

Green Organic Chemistry

Ch 2: Identification & Evaluation of Chemical Hazards

Ch 3: Chemical Exposure & Environmental Contamination

7

Nov  10

GOC Exp 4 Preparation & Distillation of Cyclohexene

Liq-liq extraction,

drying agents,

boiling point determination,

Green Principles

Safer Reagents

Solvent-free synthesis

Techniques in Organic Chemistry

Ch 11: Boiling Points

Green Organic Chemistry

Ch 8: Reaction Design & Efficiency

8

Nov.  17

GOC Exp 4 Cont:

IR

Gas Chromatography

Techniques in Organic Chemistry

Ch 16:Gas Chromatography

9

Nov.  24

äVäV

Thur /Fri Nov 27-28

äVäV

Handout: Isolation of Caffeine from Tea

äVäVäVäVäVäVä

Thanksgiving:  In everything give thanks…..

äVäVäVäVäVäVä

Extraction & Washing

Sublimation

Green Principles

Less Hazardous Process

Recycle Solvents

Safer Solvents & Auxiliaries

Techniques in Organic Chemistry

Ch 5:Measuring Mass and Volume

Ch 8: (8.1-8.5); Extraction

Ch 9: (9.1-9.6); Recrystallization

Green Organic Chemistry

Ch 5: Introduction to Green Chemistry

Ch 6: Alternative Solvents

10

Dec  1

Finish up/Clean up

Lab Quiz

11

Dec 8-9